I am a retired ER physician and father of many. After graduating from Chicago Medical School in 1990, I embarked on a 23-year career in Emergency Medicine. Medical interests include wilderness medicine, addictionology, and trauma psychology. I currently teach health and medicine online. DISCLAIMER: Accept all medical advice with a jaundiced eye. Before following my suggestions, do your own research and consult with your physician first. Enjoy & Learn!
My Quora Answer to "What Does Sepsis Feel Like?"
Honestly, I only had a handful of septic patients. If you count them as "Lives I've Saved," that puts me past 100. Not brag. Just fact:
To the patient, they all felt like they were burning in Hell. Because sepsis also causes neurological problems, a lot of them reported hallucinations. Being in Hell was one of them.
https://bit.ly/3GRVDlz
We used methylene blue to test dialyzers when I worked at Baxter-Travenol Labs in Round Lake, IL a few lifetimes ago. If I had known then when I know now, I would have been taking it daily since. Dosing is in the article.
The article is the transcript of an interview with Scott Sherr, M.D. entitled "Methylene Blue – The Magic Blue Pill for Energy and Brain Performance." I edited this excerpt for clarity.
It is well worth your time to read, especially if you are concerned about Aging Gracefully:
“Methylene blue is one of these very unique compounds that helps you make more energy in your mitochondria which is the powerhouse, the energy production center of your cell. But at the same time, it also increases antioxidant capacity… The electron transport chain is just an energy gradient that is created in your mitochondria so that you can make energy. And what you need for that to happen are electrons. And these come from our food, but they can come from molecules like methylene blue that donate electrons to the electron transport chain, induce the gradient, which allows you to make more energy. And that is how it works. Interestingly enough, there are other things that also donate electrons to the complex four. One of the major things is red light, near-Infrared light at 660 nanometers does the same thing.”
A name for the 4th Baby Step in "Aging Gracefully" eludes me. The previous one is Adult Steps, but I want to go beyond it. I think "Anti-Aging Steps" could work, especially since my recommendations include cutting-edge techniques for longevity.
This then is my first entry into the 4th Step:
NAD+, or nicotinamide adenine dinucleotide, is a coenzyme that is involved in many cellular processes, such as energy metabolism, DNA repair, and immune function. NAD+ levels decline with age, and this may contribute to various age-related diseases and conditions. Some of the potential health benefits of NAD Plus are:
It may slow down aging by activating sirtuins, a group of proteins that regulate gene expression and cellular health.
It may increase energy by enhancing mitochondrial function, the powerhouses of the cells.
It may improve cognitive function by protecting neurons from oxidative stress and inflammation.
It may reduce cholesterol by modulating lipid metabolism and lowering LDL (bad) cholesterol levels .
It may reduce cancer risk by repairing DNA damage and preventing genomic instability.
The optimal dosage of NAD+ supplements is not yet established, as different forms of NAD precursors may have different bioavailability and efficacy. However, some studies have suggested that doses ranging from 100 mg to 1000 mg per day may be effective and safe for most people. The most common forms of NAD precursors are nicotinic acid (NA), nicotinamide riboside (NR), nicotinamide (NAM), and nicotinamide mononucleotide (NMN). Each of these forms has its own advantages and disadvantages, such as side effects, cost, and absorption rate. Therefore, it is advisable to consult with a healthcare professional before taking any Niacin-related supplements.
